Human derived collagen, under the brand names CosmoDerm and CosmoPlast, is a dermal filler used to fill existing lines and add fullness to soft tissues. These injectables essentially replace and reinforce the structure of the skin, returning it to its plump, youthful appearance. CosmoDerm and CosmoPlast last two to four months depending on the location and quantity of filler used. Results are immediate with little swelling or bruising. The original collagen filler, bovine collagen, launched in the 1980s under the names Zyderm and Zyplast, is also available with similar properties and outcomes to human derived collagen, however it requires a pre-treatment allergy test two or more weeks prior to your injections.